Dr. Kozarov founded Vascular Research Foundation in 2007 to advance innovative diagnostics, prevention and treatment approaches to the leading cause of death in the U.S. and the other industrialized countries.
He has been involved with biomedical research for over 25 years, in both Europe and the U.S.
Dr. Kozarov has been a faculty member at leading medical research centers in Florida and North Carolina; he is currently an Associate Professor at Columbia University - Presbyterian Medical Center, New York City.
Dr. Kozarov has numerous local and national awards, including from the National Institutes of Health – National Heart, Lung and Blood Institute and from the American Heart Association.
SELECTED PUBLICATIONS AND PRESENTATIONS:
E. Kozarov, H. van der Wel, M. Field, M. Gritzali, R. Brown, Jr. and C. West. Characterization of FP21, a Cytosolic Glycoprotein from Dictyostelium. J. Biol. Chem. 1995, 270 (7): 3022-3030.
C. West, T. Scott-Ward, P. Teng-Umnuay, H. van der Wel, E. Kozarov and A. Huynh. Purification and Characterization of an α1,2-L-Fucosyltransferase Which Modifies the Cytosolic Protein FP21, from the Cytosol of Dictyostelium. J. Biol. Chem. 1996, 271 (20): 12024-12035.
C. West, E. Kozarov, P. Teng-Umnuay. The cytosolic glycoprotein FP21 of Dictyostelium discoideum is encoded by two genes resulting in a polymorphism at a single aminoacid position. Gene, 1997, 200 (1): 1-10.
E. Kozarov, J. Whitlock, H. Dong, E. Carrasco and A. Progulske-Fox. The number of direct repeats in hagA is variable among Porphyromonas gingivalis strains. Infection and Immunity, 1998, 66 (10): 4721-4725.
A. Progulske-Fox, E. Kozarov, B. Dorn, W. Dunn, J. Burks and Y. Wu. Porphyromonas gingivalis Virulence Factors and Invasion of Cells of the Cardiovascular System. J. Periodontal Research, 1999, 34:1-7.
E. Kozarov, N. Miyashita, J. Burks, K. Cerveny, T. A. Brown, W. P. McArthur and A. Progulske-Fox. Expression and Immunogenicity of Hemagglutinin A from Porphyromonas gingivalis in an Avirulent Salmonella enterica Serovar Typhimurium Vaccine Strain. Infect Immun. 2000, 68(2):732-739.
M. L. Van Tilburg, E. Kozarov, A. Progulske-Fox, and L.J. Brady. The Effect of Monoclonal Antibody and Route of Immunization on the Humoral Immune Response Against Porphyromonas gingivalis. Oral Microbiol Immunol 2001, 16(3):153-62.
Y. Song, E. Kozarov, M. Handfield, S. Cao, S. Walters, J. Hillman and A. Progulske-Fox. Genes of Periodontopathogens Expressed During Human Disease. Annals Periodontol. 2002 7(1), 38-42.
E. Kozarov, B. Dorn, C. E. Shelburne, W. A. Dunn, Jr., and A. Progulske-Fox. Human Atherosclerotic Plaque Contains Viable Invasive Actinobacillus actinomycetemcomitans and Porphyromonas gingivalis. Arteriosclerosis, Thrombosis and Vascular Biology 2005 Mar; 25(3):e17-8.
H. Song, M. Belanger, J. Whitlock, E. Kozarov and A. Progulske-Fox. Hemagglutinins B is Involved in the Adherence of P. gingivalis to Human Coronary Artery Endothelial Cells. Infect. Immun. 2005 Nov;73(11):7267-73.
E. Kozarov, D. Sweier, C. Shelburne, A. Progulske-Fox, D. Lopatin. Detection of Bacterial DNA in Atheromatous Plaques by Quantitative PCR. Microbes and Infection, 2006 Mar;8(3):687-93.
L. Li, R. Michel, J. Cohen, A. DeCarlo and E. Kozarov. Intracellular survival and vascular cell-to-cell transmission of P. gingivalis. BMC Microbiology 2008, 8:26.
PRESENTATIONS:
E. Kozarov. Construction of Expression Vector Active in Prokaryotic Cells. XVI International Congress of Genetics, Toronto, August 1988, 31.13.16.
E. Kozarov, A. Kaliev. Plant Promoter-Like Fragment Ensures Marker Gene Expression in Both Bacterial and Plant Cells. N.A.T.O. Advanced Study Institute/F.E.B.S. Workshop, May 14-23 1990, Schloss Elmau, Bavaria, Germany.
C. M. West, E. Kozarov, Melvin Field. Characterization of a Cytosolic Glycoprotein in Dictyostelium. International Dictyostelium Conference, University of California, San Diego, August 21-26, 1994.
C. West, E. Kozarov, T. Scott-Ward, P. Teng-Umnuay, H. van der Wel, R. D. Brown & M. Gritzali. Characterization of a Cytosolic Glycoprotein in Dictyostelium. Gordon Conference, Ventura, California, February 1995.
C. M. West, E. Kozarov, H. van der Wel, T. Scott-Ward, P. Teng-Umnuay. Dissection of a Cytosolic Glycosylation Pathway in Dictyostelium discoideum. Glycotechnology Conference, San Diego, December 1995.
C. M. West, P. Teng-umnuay, E. Kozarov & M. Bubb. "Characterization of a Cytosolic Glycosylation Pathway in the Cellular Slime Mold Dictyostelium discoideum" Gordon Conference on Glycobiology, Ventura, CA, February 2-7, 1997.
E. Kozarov, J. Whitlock, A. Progulske-Fox. HArep Unit Number Variability in Hemagglutinin A from Different P. gingivalis Strains. J. Dent. Res. 1997, 76:224.
E. V. Kozarov, N. Miyashita, J. N. Burks and A. Progulske-Fox. Expression of Hemagglutinin A from Porphyromonas gingivalis in Escherichia coli and in an Avirulent Vaccine Strain of Salmonella typhimurium. J. Dent. Res. 1998. 77:855.
J. Battle, E. Kozarov, M. Handfield, F. Meng, A. Progulske-Fox. Isolation of A. actinomycetemcomitans virulence proteins using a genetic approach. University of Florida College of Dentistry's 1998 Student Summer Research Fellowship Presentation, Gainesville, Florida, August 27th, 1998.
E. Kozarov, A. Progulske-Fox and J. Hillman. Use of a PhoA Fusion Expression Vectors for Analysis of Porphyromonas gingivalis Pathogenicity. J. Dent. Res. 1999. 78:506.
J. Whitlock, B. Dorn, J. Burks, E. Kozarov, A. Progulske-Fox. Porphyromonas gingivalis hagB/C hemagglutinin mutant exhibits reduced invasion of human oral epithelial cells. J. Dent. Res. 1998. 77:855.
B. Dorn, E. Kozarov, and A. Progulske-Fox. Invasion of HUVEC and KB Cells by Porphyromonas gingivalis Strains. J. Dent. Res. 1999. 78:506.
E. Kozarov, J. Hillman & A. Progulske-Fox. Identification of Virulence Genes in Porphyromonas gingivalis by Genomic Analysis. ASM 99th General Meeting, May 30 - June 3, 1999, Chicago, B/D-3.
A. Progulske-Fox, E. Kozarov, B. Dorn, W. Dunn, J. Burks and Y. Wu. Porphyromonas gingivalis Virulence Factors and Invasion of Cells of the Cardiovascular System. 11th International Conference on Periodontal Research, 1999.
A. Lewis, A. Progulske-Fox and E. Kozarov*. Putative Type III Secretion System Regulator. University of Florida College of Medicine, 1999.
C. Nowacki, E. Kozarov* and A. Progulske-Fox. Expression, Purification and Immunological Properties of Recombinant Hemagglutinin A from Porphyromonas gingivalis. University of Florida College of Dentistry, 1999.
M. L. Van Tilburg, E. Kozarov, and L.J. Brady. Effect of Route of Immunization and Complexing Bacteria with Monoclonal Antibody on the Mucosal Immune Response Against Porphyromonas gingivalis. J. Dent. Res. 2000. 79:309.
E. Kozarov, C. Nowacki and A. Progulske-Fox. Expression, Purification, Immunological and Functional Properties of Recombinant Hemagglutinin A from Porphyromonas gingivalis. J. Dent. Res. 2000. 79:394.
E. Kozarov, Y.-H. Song and A. Progulske-Fox. Receptors for Hemagglutinin A from Porphyromonas gingivalis on Human Endothelial and Epithelial Cells. ASM 100th General Meeting, Los Angeles, May 21-25, 2000.
Y.-H. Song, E. Kozarov*, A. Skipper, K. Totten, A. Ogen, M. Handfield, J. Hillman and A. Progulske-Fox. Probing for in vivo induced Porphyromonas gingivalis virulence genes using IVIAT. ASM 101th General Meeting, Orlando, May 20-24, 2001.
E. Kozarov, D. Siemann, Y. Song, A. Valle, D. Rooke and A. Progulske-Fox. Molecular Mechanisms of Endothelial Destruction by P. gingivalis. J. Dent. Res. 2002, 81:54.
J.N. Burks, C.T. Wujick, L.M. Marshall, E. Kozarov, and A. Progulske-Fox. Function of the Porphyromonas gingivalis DNA Adenine Methylase in the Expression of Virulence. J. Dent. Res. 2002, 81:497.
Progulske-Fox, M. Handfield, S. Cao, S. Walters, Y. Song, E. Kozarov and J. Hillman. Genes of Periopathogens Expressed During Human Disease. ICPR, June 2002, Chapel Hill, NC.
E. Kozarov. Prevention and treatment of periodontal disease by propolis and its components. BioFlorida Biotech Conference, Boca Raton, March 13, 2003.
Kozarov E., Shelburne C.E., Song Y., Progulske-Fox A. and Lopatin D.E. Detection of Bacterial DNA in Atheromatous Plaques by Quantitative PCR. American Heart Association, 4th Annual Conference on Arteriosclerosis, Thrombosis and Vascular Biology, May 8-10, 2003, Washington, D.C.
E. Kozarov, L. Li, A. DeCarlo, R. Rodriguez, R. Michel, H. Song and A. Progulske-Fox. Effects of Porphyromonas gingivalis Secreted Proteins on Human Primary Endothelial Cells, ASM 103rd General Meeting, Washington, D.C., May 18-22, 2003.
H. Song, E.V. Kozarov*, M. Handfield, M. Bélanger, and A. Progulske-Fox. HagB is involved in the adherence of P. gingivalis to Human Coronary Artery Endothelial Cells. International Association for Dental Research, Göteborg, June 2003. J. Dent. Res. 2003, 82B: 280.
E. Kozarov, L. Li, R. Michel, R. E. Rodriguez and A. A. DeCarlo. Differential Activity of Porphyromonas gingivalis Secreted Proteins toward Polarized Human Endothelial Cells. International Association for Dental Research, Göteborg, June 2003. J. Dent. Res. 2003, 82B: 180.
E. Kozarov, A. Progulske-Fox, J. Burks, L. Li and D. Siemann. Bacterial Proteinase-Mediated Human Cell Proliferation Inhibition. Florida Research Consortium, May 17, 2004, St. Petersburg, FL.
K. Munoz and E. Kozarov*. Association of Bacterial Adhesin with Invasion of Human Cells. American Society of Microbiology, General Meeting 2005, Atlanta, June 2005.
H. Song, E. Kozarov, M. Bélanger, and A. Progulske-Fox. Hemagglutinin A Participates in Adhesion and Invasion to HCAEC. International Association for Dental Research, March 2005, Baltimore.
E. Kozarov, Brian R. Dorn, Raynald Michel, Charles E. Shelburne, William A. Dunn, Jr., and Ann Progulske-Fox. Human Atherosclerotic Plaque Contains Viable Invasive Actinobacillus actinomycetemcomitans and Porphyromonas gingivalis. FL ASM, Fort Lauderdale, April 2005.
INVITED SPEAKER:
Columbia University of the City of New York, 2007
University of West Virginia, 2007
UMDNJ, Newark, NJ, 2006
University of Louisville, KY, 2006
Harvard/ Forsyth Institute, Boston, Massachusetts, 2006
Pfizer, Inc., Morris Plains, New Jersey, 2006
Fraunhofer USA, Inc., Newark, Delaware, 2005
New York University, New York, 2004
University of Milano, 2004
Ludwig-Maximilians-Universität, Munich, 2004
Sunol Inc., Miami, Florida, 2000
Cleveland Clinic Foundation, Fort Lauderdale, 2000
